It was created in 1991 and was formerly part of the Tororo District.
The district boarders the districts of Mbale in the east, Kumi in the north, Kamuli in the west, Tororo and Iganga in the south and Soroti in the north-west.
The district has over 522,254 people, 269,224 are female and 253,030 are
There is Agriculture with main emphasis on food crops such as millet, potatoes, beans, bananas, Simsim and sunflower. Cash crops like cotton.
Banks; Stanbic Bank Uganda Ltd.
The district has 4 Government dispensaries (II), 22 health centres (III) at county, 3 health centres (IV) at sub-district with 1 hospital. More so, it has 6 private/NGO dispensaries, 22 clinics, 6 health centres (III) and no hospital.
There is a Government hospital at Pallisa with a total of 109 beds.
The district has a total of 197 primary schools with 183 government, 9 private and 5 community schools. For secondary schools, the district has over 37 schools, 15 are government, 16 private and 6 community